MovDisordV3, Main, Exploration, bibRecord, 000119

Plasma oligomeric alpha-synuclein is associated with glucocerebrosidase activity in Gaucher disease.

Identifieur interne : 000119 ( Main/Exploration ); précédent : 000118; suivant : 000120

Plasma oligomeric alpha-synuclein is associated with glucocerebrosidase activity in Gaucher disease.

Auteurs : Evgenii Nuzhnyi [Russie] ; Anton Emelyanov [Russie] ; Tatyana Boukina [Russie] ; Tatiana Usenko [Russie] ; Andrey Yakimovskii [Russie] ; Ekaterina Zakharova [Russie] ; Sofya Pchelina [Russie]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.

RBID : pubmed:25962734

Abstract

The link between Parkinson's disease (PD) and Gaucher disease (GD), the most common lysosomal storage disease associated with loss of glucocerebrosidase (GBA) activity, can be explained by abnormal accumulation of oligomeric alpha-synuclein (α-Syn) species resulting from mutations in the GBA gene. However, in GD, the relationship between GBA activity and α-Syn accumulation in biological fluids has not been investigated.

DOI: 10.1002/mds.26200
PubMed: 25962734

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Plasma oligomeric alpha-synuclein is associated with glucocerebrosidase activity in Gaucher disease.</title>
<author><name sortKey="Nuzhnyi, Evgenii" sort="Nuzhnyi, Evgenii" uniqKey="Nuzhnyi E" first="Evgenii" last="Nuzhnyi">Evgenii Nuzhnyi</name>
<affiliation wicri:level="1"><nlm:affiliation>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg</wicri:regionArea>
<wicri:noRegion>St. Petersburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Emelyanov, Anton" sort="Emelyanov, Anton" uniqKey="Emelyanov A" first="Anton" last="Emelyanov">Anton Emelyanov</name>
<affiliation wicri:level="1"><nlm:affiliation>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg</wicri:regionArea>
<wicri:noRegion>St. Petersburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Boukina, Tatyana" sort="Boukina, Tatyana" uniqKey="Boukina T" first="Tatyana" last="Boukina">Tatyana Boukina</name>
<affiliation wicri:level="3"><nlm:affiliation>Medical-genetics Scientific Center, Moscow, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>Medical-genetics Scientific Center, Moscow</wicri:regionArea>
<placeName><settlement type="city">Moscou</settlement>
<region>District fédéral central</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Usenko, Tatiana" sort="Usenko, Tatiana" uniqKey="Usenko T" first="Tatiana" last="Usenko">Tatiana Usenko</name>
<affiliation wicri:level="1"><nlm:affiliation>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg</wicri:regionArea>
<wicri:noRegion>St. Petersburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Yakimovskii, Andrey" sort="Yakimovskii, Andrey" uniqKey="Yakimovskii A" first="Andrey" last="Yakimovskii">Andrey Yakimovskii</name>
<affiliation wicri:level="1"><nlm:affiliation>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg</wicri:regionArea>
<wicri:noRegion>St. Petersburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zakharova, Ekaterina" sort="Zakharova, Ekaterina" uniqKey="Zakharova E" first="Ekaterina" last="Zakharova">Ekaterina Zakharova</name>
<affiliation wicri:level="3"><nlm:affiliation>Medical-genetics Scientific Center, Moscow, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>Medical-genetics Scientific Center, Moscow</wicri:regionArea>
<placeName><settlement type="city">Moscou</settlement>
<region>District fédéral central</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pchelina, Sofya" sort="Pchelina, Sofya" uniqKey="Pchelina S" first="Sofya" last="Pchelina">Sofya Pchelina</name>
<affiliation wicri:level="1"><nlm:affiliation>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg</wicri:regionArea>
<wicri:noRegion>St. Petersburg</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2015">2015</date>
<idno type="RBID">pubmed:25962734</idno>
<idno type="pmid">25962734</idno>
<idno type="doi">10.1002/mds.26200</idno>
<idno type="wicri:Area/PubMed/Corpus">000173</idno>
<idno type="wicri:Area/PubMed/Curation">000173</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000119</idno>
<idno type="wicri:Area/Ncbi/Merge">004345</idno>
<idno type="wicri:Area/Ncbi/Curation">004345</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">004345</idno>
<idno type="wicri:Area/Main/Merge">000119</idno>
<idno type="wicri:Area/Main/Curation">000119</idno>
<idno type="wicri:Area/Main/Exploration">000119</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Plasma oligomeric alpha-synuclein is associated with glucocerebrosidase activity in Gaucher disease.</title>
<author><name sortKey="Nuzhnyi, Evgenii" sort="Nuzhnyi, Evgenii" uniqKey="Nuzhnyi E" first="Evgenii" last="Nuzhnyi">Evgenii Nuzhnyi</name>
<affiliation wicri:level="1"><nlm:affiliation>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg</wicri:regionArea>
<wicri:noRegion>St. Petersburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Emelyanov, Anton" sort="Emelyanov, Anton" uniqKey="Emelyanov A" first="Anton" last="Emelyanov">Anton Emelyanov</name>
<affiliation wicri:level="1"><nlm:affiliation>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg</wicri:regionArea>
<wicri:noRegion>St. Petersburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Boukina, Tatyana" sort="Boukina, Tatyana" uniqKey="Boukina T" first="Tatyana" last="Boukina">Tatyana Boukina</name>
<affiliation wicri:level="3"><nlm:affiliation>Medical-genetics Scientific Center, Moscow, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>Medical-genetics Scientific Center, Moscow</wicri:regionArea>
<placeName><settlement type="city">Moscou</settlement>
<region>District fédéral central</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Usenko, Tatiana" sort="Usenko, Tatiana" uniqKey="Usenko T" first="Tatiana" last="Usenko">Tatiana Usenko</name>
<affiliation wicri:level="1"><nlm:affiliation>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg</wicri:regionArea>
<wicri:noRegion>St. Petersburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Yakimovskii, Andrey" sort="Yakimovskii, Andrey" uniqKey="Yakimovskii A" first="Andrey" last="Yakimovskii">Andrey Yakimovskii</name>
<affiliation wicri:level="1"><nlm:affiliation>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg</wicri:regionArea>
<wicri:noRegion>St. Petersburg</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zakharova, Ekaterina" sort="Zakharova, Ekaterina" uniqKey="Zakharova E" first="Ekaterina" last="Zakharova">Ekaterina Zakharova</name>
<affiliation wicri:level="3"><nlm:affiliation>Medical-genetics Scientific Center, Moscow, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>Medical-genetics Scientific Center, Moscow</wicri:regionArea>
<placeName><settlement type="city">Moscou</settlement>
<region>District fédéral central</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pchelina, Sofya" sort="Pchelina, Sofya" uniqKey="Pchelina S" first="Sofya" last="Pchelina">Sofya Pchelina</name>
<affiliation wicri:level="1"><nlm:affiliation>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg, Russia.</nlm:affiliation>
<country xml:lang="fr">Russie</country>
<wicri:regionArea>First Pavlov's State Medical University of Saint-Petersburg, St. Petersburg</wicri:regionArea>
<wicri:noRegion>St. Petersburg</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2015" type="published">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The link between Parkinson's disease (PD) and Gaucher disease (GD), the most common lysosomal storage disease associated with loss of glucocerebrosidase (GBA) activity, can be explained by abnormal accumulation of oligomeric alpha-synuclein (α-Syn) species resulting from mutations in the GBA gene. However, in GD, the relationship between GBA activity and α-Syn accumulation in biological fluids has not been investigated.</div>
</front>
</TEI>
<affiliations><list><country><li>Russie</li>
</country>
<region><li>District fédéral central</li>
</region>
<settlement><li>Moscou</li>
</settlement>
</list>
<tree><country name="Russie"><noRegion><name sortKey="Nuzhnyi, Evgenii" sort="Nuzhnyi, Evgenii" uniqKey="Nuzhnyi E" first="Evgenii" last="Nuzhnyi">Evgenii Nuzhnyi</name>
</noRegion>
<name sortKey="Boukina, Tatyana" sort="Boukina, Tatyana" uniqKey="Boukina T" first="Tatyana" last="Boukina">Tatyana Boukina</name>
<name sortKey="Emelyanov, Anton" sort="Emelyanov, Anton" uniqKey="Emelyanov A" first="Anton" last="Emelyanov">Anton Emelyanov</name>
<name sortKey="Pchelina, Sofya" sort="Pchelina, Sofya" uniqKey="Pchelina S" first="Sofya" last="Pchelina">Sofya Pchelina</name>
<name sortKey="Usenko, Tatiana" sort="Usenko, Tatiana" uniqKey="Usenko T" first="Tatiana" last="Usenko">Tatiana Usenko</name>
<name sortKey="Yakimovskii, Andrey" sort="Yakimovskii, Andrey" uniqKey="Yakimovskii A" first="Andrey" last="Yakimovskii">Andrey Yakimovskii</name>
<name sortKey="Zakharova, Ekaterina" sort="Zakharova, Ekaterina" uniqKey="Zakharova E" first="Ekaterina" last="Zakharova">Ekaterina Zakharova</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000119 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000119 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:25962734
   |texte=   Plasma oligomeric alpha-synuclein is associated with glucocerebrosidase activity in Gaucher disease.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:25962734" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a MovDisordV3

This area was generated with Dilib version V0.6.23.
Data generation: Sun Jul 3 12:29:32 2016. Site generation: Wed Feb 14 10:52:30 2024

Movement Disorders (revue)

Plasma oligomeric alpha-synuclein is associated with glucocerebrosidase activity in Gaucher disease.

Plasma oligomeric alpha-synuclein is associated with glucocerebrosidase activity in Gaucher disease.

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.